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Fungi Extract (Alternaria Alternata)

Fungi Extract (Alternaria Alternata)

Item # Pack Size
4-AT-001 1 mL
Antigen Alternaria Alternata
Material Powder of mold, Alternaria Alternata
Standard ・The major allergen and total proteins vary depending on the lot because of production to order.
Please contact us the details.
・Only total protein concetration was determined, using the Lowry method with BSA as a standard.
・Lyophilized.
・Add 1.0 mL distilled water (or equivalent). It will become phosphate buffered saline [PBS] (pH7.4), solution.
Components Extracts from Fungi Extract (Alternaria Alternata) (filtered with membranfilter, pore size 0.45 µm), Phosphate-buffered Saline, Contains preservatives
Storage Store at 2-8℃
Don’t leave at room temperature for long periods of time.
Avoid repeating freezing and thawing.
Note This product is a reagent for experimens.
Cannot be used for treatment and diagnosis purposes.
  • ■ Reference

    1) Miyajima K, et al. Direct analysis of airborne mite allergen (Der f1) in the residential atmosphere by chemifluorescent immunoassay using bioaerosol sampler. Talanta 2014; 123: 241–246. [Pubmed]

    2) ElRamlawy KG, et al. Der f 34, a novel major house dust mite allergen belonging to a highly conserved Rid/YjgF/YER057c/UK114 family of imine deaminases. J Biol Chem 2016; 291(41): 21607-21615. [Pubmed]

    3) Morikawa T, et al. Activation of group 2 innate lymphoid cells exacerbates and confers corticosteroid resistance to mouse nasal type 2 inflammation. Int Immunol 2017; 29(5): 221-233. [Pubmed]

    4) Okunishi K, et al. Exophilin-5 regulates allergic airway inflammation by controlling IL-33–mediated Th2 responses J Clin Invest 2020; 130(7): 3919–3935. [Pubmed]

    5) Naito M, et al. Semaphorin 6D-expressing mesenchymal cells regulate IL-10 production by ILC2s in the lung. Life Sci Alliance 2022; 5(11): e202201486. [Pubmed]

    6) Inoue H, et al. Comprehensive Gene Expression Signature Using RNA-Seq in Airways of Mouse Model of Severe Asthma with Fungal Sensitization. Int Arch Allergy Immunol 2022; 183(2): 142–152. [Pubmed]

    7) Nomura A, et al. Identification of a novel enhancer essential for Satb1 expression in TH2 cells and activated ILC2s. Life Sci Alliance 2023; 6(8): e202301897. [Pubmed]

    8) Okuyama K, et al. The Majority of the Serine/Threonine Phosphorylation Sites in Bcl11b Protein Are Dispensable for the Differentiation of T Cells. J Immunol 2023; 210(11): 1728–1739. [Pubmed]

    9) Shimizu Y, et al. Mucosal-associated invariant T cells repress group 2 innate lymphoid cells in Alternaria alternata-induced model of allergic airway inflammation. Front Immunol 2022; 13: 1005226. [Pubmed]

    10) Fukuoka S, et al. Mechanoreceptor Piezo1-Mediated Interleukin Expression in Conjunctival Epithelial Cells: Linking Mechanical Stress to Ocular Inflammation. bioRxiv 2024; 2024–06.

Note

All products that ITEA sells are reagent for experiment.
Cannot be used for treatment and diagnosis purposes.
We do not sell our products to individuals.