学術論文

1. Yoshikawa, Y., Yamonouchi, K., Morikawa, Y. and Sakaguchi, M. Characterization of canine distemper viruses adapted to neural cells and their neurovirulence in mice.Microbiology and Immunology 27, 503-513, 1983.

2. Sakaguchi, M. , Yoshikawa, Y. and Yamanouchi, K.: Growth of measles and subacute sclerosing panencephalitis viruses in human neural cell lines. Microbiology and Immunology 28, 461-469, 1984.

3. Sakaguchi, M. , Yoshikawa, Y., Yamanouchi, K. and Takeda, K.: Growth of defective subacute sclerosing panencephalitis viruses in human neural cells and their neurovirulence in mice. Journal of General Virology 66, 373-377, 1985.

4. 小船冨美夫，坂田宏子，棚林　清，佐藤　威，小浜友昭，茅野文利，杉浦　昭， 阪口雅弘 分離された麻疹ウイルス株の性状. 臨床とウイルス 13, 312-315, 1985.

5. 井上　栄， 阪口雅弘 ，掘　幹朗，渡辺恒明: IgE 抗体測定によるスギ花粉症の疫学的研究． 医学のあゆみ 136, 959-960, 1986.

6. Sakaguchi, M. , Yoshikawa, Y., Yamanouchi, K., Takeda, K. and Sato, T.: Characteristics of fresh isolates of wild measles virus. Japanese Journal of Experimental Medicine 56, 61-67, 1986.

7. 阪口雅弘 ，井上　栄，鈴木修二: 蛍光 enzyme-linked immunosorbent assay による抗スギ花粉IgE抗体の測定．アレルギー 35, 233-237, 1986.

8. 井上　栄， 阪口雅弘 ，母里啓子，宮村紀久子，氏家淳雄，重原　進，野口有三: スギ花粉症の血清疫学調査ーIgE抗体保有者の近年における増加ー 医学のあゆみ 138, 285-286, 1986.

9. Tamura, S., Kobayasi, T., Kikuta, K., Nakagawa, M., Sakaguchi, M. . and Inouye, S.: IgE antibody responses against Japanese cedar pollen in the mouse. Microbiology and Immunology 30, 883-891, 1986.

10. Sakaguchi, M. , Yoshikawa, Y., Yamanouchi, K., Sata, T., Nagashima, K. and Takeda, K.: Growth of measles virus in epithelial and lymphoid tissues of cynomolgus monkeys. Microbiology and Immunology 30, 1067-1073, 1986.

11. Sata, T., Kurata, Y., Aoyama, Y., Sakaguchi, M. , Yamanouchi, K. and Takeda, K.: Analysis of viral antigens in giant cells of measles pneumonia by immunoperoxidase method. Virchows Archiv 410, 133-138, 1986.

12. Sakaguchi, M. and Inouye, S.: Fluorometric enzyme-linked immunosorbent assay for the measurement of IgE antibody to mite Dermatophagoides farinae. Microbiology and Immunology 31, 711-715, 1987.

13. 阪口雅弘 ，井上　栄，吉沢　晋，池田耕一: 蛍光サンドイッチ Enzyme-Linked Immunosorbent Assay による空気中スギ花粉量の測定．アレルギー 36, 886-889, 1987.

14. 井上　栄， 阪口雅弘 ，森田盛大， 庄司俊雄，金田誠一，木村栄二， 山本保男, 井上博雄，小野哲朗，道家　直，平川浩資: 一般住民のスギ花粉特異的IgE 抗体保有率の地域差． 医学のあゆみ 145, 121-122, 1988.

15. Miyazawa, H., Inouye S., Sakaguchi, M. and Koizumi, K.: A reverse-sandwich ELISA for IgG antibody to a pollen allergen. Journal of Allergy and Clinical Immunology 82, 407-413, 1988.

16. Miyazawa, H., Inouye S., Sakaguchi, M. and Koizumi, K.: A reverse-sandwich ELISA for IgG antibody to a pollen allergen. Journal of Allergy and Clinical Immunology 82, 407-413, 1988.

17. Sakaguchi, M. , Inouye, S., Miyazawa, H., Kamimura, H., Kimura, M. and Yamazaki, S.: Evaluation of dust respirators for elimination of mouse aeroallergens. Laboratory Animal Science 39, 63- 66, 1989.

18. Sakaguchi, M. , Inouye, S., Miyazawa, H. and Tamura, S.: Measurement of antigen-specific mouse IgE by a fluorometric reverse (IgE-capture) ELISA. Journal of Immunological Methods 116, 181-187, 1989.

19. Sakaguchi, M. , Inouye, S., Miyazawa, H., Kamimura, H., Kimura, M. and Yamazaki,S.: Particle size of airborne mouse crude and defined allergens. Laboratory Animal Science 39, 234-236, 1989.

20. Taniguchi, Y., Ikegami, H., Usui, M., Ando, S., Kurimoto, M., Sakaguchi, M. , Inouye, S. and Matuhasi, T.: Biological and Immunological properties of sugi basic protein- conjugate. I. Suppressive effect on IgE antibody production and on IgE-mediated reactions. International Archives of Allergy and Applied Immunology 89, 136-142, 1989.

21. 内村公昭，赤坂　徹，尾川勝彦，岡田文寿，鈴木五男，前田和一， 阪口雅弘 ，井上　栄: 気管喘息児におけるチリダニとスギ特異的ＩｇＥ抗体の年齢別感作状況について ーRadioallergosorbent Test および Enzyme-Linked Immunosorbent Assay の比較ー　アレルギー 38, 451-458, 1989.

22. Sakaguchi, M. , Inouye, S., Yasueda, H., Irie, T., Yoshizawa, S. and Shida, T.: Measurement of allergens associated with dust mite allergy. II. Concentrations of airborne mite allergens (Der I and Der II) in the house. International Archives of Allergy and Applied Immunology 90, 190-193, 1989.

23. Takahashi, Y., Mizoguchi, J., Katagiri S., Sakaguchi, M. , Inouye, S., Ishikawa M., Tonosaki, A. and Iwao, F.: Development and distribution of the major pollen allergen (Cry j I) in male flower buds of Japanese cedar (Cryptomeria japonica). Japanese Journal of Allergology 38, 1354-1358, 1989.

24. Fukuhara, M., Mizokami, K., Sakaguchi, M. , Niimura, Y., Kato, K., Inouye, S. and Tanaka, A.: Aflatoxin B1-specific cytochrome P-450 isozyme (P-450-AFB) inducible by 3-methylcholanthrene in golden hamsters. Biochemical Pharmacology 39, 463-469, 1990.

25. Sakaguchi, M. , Inouye, S., Taniai, M., Ando, S., Usui, M. and Matuhasi, T.: Identification of the second major allergen of Japanese cedar pollen. Allergy 45, 309-312, 1990.

26. 鈴木修二，田所憲治，中島一格，高藤　繁，小浜　肇，玉川鐡雄， 阪口雅弘 ，井上　栄，宮沢　博: 東京都内勤務者におけるスギ花粉症症状と特異的IgE 抗体の経時変化．医学のあゆみ154, 205-206, 1990.

27. Sakaguchi, M. , Inouye, S., Miyazawa, H., Kamimura, H., Kimura, M. and Yamazaki, S.: Evaluation of Countermeasures for reduction of mouse airborne allergens. Laboratory Animal Science 40, 613-615, 1990.

28. 高橋裕一，井上　栄， 阪口雅弘 ，片桐　進: イムノブロット法による空中スギ、イネ科植物花粉アレルゲン粒子数の測定．アレルギー 39, 1612-1620, 1990.

29. 吉沢　晋，菅原文子，安枝　浩，信太隆夫，入江建久， 阪口雅弘 ，井上　栄 : 空中ダニ主要アレルゲン（Der I, Der II）の粒子径分布と空気中からの減衰. アレルギー 40, 435-438, 1991.

30. 阪口雅弘 ，井上　栄，吉沢　晋，菅原文子，入江建久，安枝　浩，信太隆夫，今井智子: 布団内ダニアレルゲンの除去方法の評価． アレルギー 40, 439-443, 1991.

31. Takahashi, Y., Sakaguchi, M. , Inouye, S., Miyazawa, H., Imaoka, K., and Katagiri, S.: Existence of exine-free allergen particles of Japanese cedar (Cryptomeria japonica) pollen. Allergy 46, 588-593, 1991.

32. 入江建久， 阪口雅弘 ，難波英敬，藤野茂行，小峰裕己，安枝　浩，二宮保男: 住居におけるダニアレルゲンの挙動に関する研究． 公衆衛生研究 40, 318-326, 1991.

33. Sakaguchi, M. , Inouye, S., Yasueda, H. and Shida, T.: Concentration of airborne mite allergens (Der I and Der II) during sleep. Allergy 47, 55-57, 1992.

34. 大谷武司，木村康子， 阪口雅弘 ，井上　栄，飯倉洋治，安枝　浩: 特殊防ダニ布団によるダニおよびダニアレルゲンの管理．アレルギー 41, 411-417, 1992.

35. 高橋裕一，吉村俊一，真砂　央，井上浩三，白井　忠，名古屋隆生， 阪口雅弘 ，井上栄，片桐　進: 蛍光抗体染色法とフロ−サイトメトリ−を組み合せた空中スギ花粉量の迅速測定法．アレルギー 41, 1611-1613, 1992.

36. Sakaguchi, M. , Inouye, S., Imaoka, K., Miyazawa, H., Hashimoto, M., Nigi, H., Nakamura, S., Gotoh, S., Minezawa, M., Fujimoto, K., Honjo, S., Taniguchi, Y. and Ando, S.: Measurement of serum IgE antibodies against Japanese cedar pollen (Cryptomeria japonica) in Japanese monkeys (Macaca fuscata) with pollinosis. Journal of Medical Primatology 21, 323-327, 1992.

37. Takahashi, Y., Nagoya, T., Watanabe, M., Inouye, S., Sakaguchi, M. and Katagiri, S.: A new method of counting airborne Japanese cedar (Cryptomeria japonica) pollen allergens by immunoblotting. Allergy 48, 94-98, 1993.

38. 今岡浩一， 阪口雅弘 ，井上　栄: スギ花粉アレルゲン免疫ラットにおけるIgE抗体応答．実験動物 42, 61-65, 1993.

39. Takahashi, Y., Sakaguchi, M. , Inouye, S., Yasueda, H., Shida, T. and Katagiri, S.: Airborne grass pollen antigens in a grassland as studied by immunoblotting with anti-Lol p I antibody. Grana 32, 302-307, 1993.

40. Takahashi, Y., Sakaguchi, M. , Inouye, S., Nagoya, T., Watanabe, M. and Yasueda, H.: Confirmation of the airborne occurrence of micron-size airborne pollen antigen carrying particles by immunoblotting. Allergie et Immunologie 25, 132-136, 1993.

41. Sakaguchi, M. , Inouye, S., Irie, T., Miyazawa, H., Watanabe, M., Yasueda, H., Shida, T., Niita H., Chapman, MD., Schou, C. and Aalberse, RC.: Airborne cat (Fel d I), dog (Can f I), and mite (Der I and Der II) allergen levels in the homes of Japan. Journal of Allergy and Clinical Immunology 92, 797-802, 1993.

42. 高橋裕一，宮沢　博， 阪口雅弘 ，井上　栄，片桐　進，名古屋隆生，渡辺政尚，谷口美文，栗本雅司，安枝　浩: 室内塵中のCry j I 量と空中スギ花粉数との関係．アレルギー 43, 97-100, 1994.

43. Hashimoto, M., Nigi, H., Sakaguchi, M. , Inouye, S., Miyazawa, H., Watanabe, M., Mitsuseki, M., Yasueda, H. and Nitta, H.: Removal of cat major allergen (Fel d I) from futon (Japanese bedding) with a home washing machine. Journal of Veterinary Medical Science 56, 597-598, 1994.

44. Yasueda, H., Saito, A., Akiyama, K., Maeda, Y., Shida, T., Sakaguchi, M. and Inouye, S.: Estimation of Der p I and Der f I quantities in the reference preparations of Dermatophagoides mite extracts. Clinical and Experimental Allergy 19, 1030-1035, 1994.

45. Sakaguchi, M. , Inouye, S., Miyazawa, H., Okabe, T., Yasueda, H., Muto, A., Tanaka, I., Akasaka, T., Wu, C.H., Chapman, M.D. and Schou, C.: Sensitization to cockroach　allergens of asthma patients in Japan. Japanese Journal of Allergology 43, 1309-1315, 1994.

46. Hashimoto, M., Sakaguchi, M. , Inouye, S., Imaoka, K., Nigi, H., Fujimoto, K., Honjo, S., Taniguchi, Y., Kurimoto, M., Gotoh, S., Minezawa, M., Yokota, A. and Nakamura, S.: Prevalence of IgE antibody to crude and purified allergens of Japanese cedar pollen among different troops of Japanese monkeys (Macaca fuscata). Journal of Medical Primatology 23, 393-396, 1994.

47. Sasaki, Y., Kitagawa, H., Fujioka, T. Kitoh, K., Iwasaki, T., Sakaguchi M. and Inouye, S.: Hypersensitivity to Japanese cedar (Cryptomeria japonica) pollen in dogs. Journal of Veterinary Medical Science 57, 683-685, 1995.

48. Hashimoto, M., Nigi, H., Sakaguchi, M. , Inouye, S., Imaoka, K., Miyazawa, H., Taniguchi, Y., Kurimoto, M., Yasueda, H. and Ogawa, T.: Sensitivity to two major allergens (Cry j I and Cry j II) in patients with Japanese cedar (Cryptomeria japonica) pollinosis. Clinical and Experimental Allergy 25, 848-852, 1995.

49. Sakaguchi, M. , Ogura, H. and Inouye, S.: IgE antibody to gelatin in children with immediate-type reactions to measles and mumps vaccines. Journal of Allergy and Clinical Immunology 96,563-565, 1995.

50. 小倉英郎，小倉由紀子，友田隆士，倉繁隆信， 阪口雅弘 ，井上　栄: 麻疹ワクチン接種後、アナフィラキシーを来したゼラチンアレルギー児の１例． 小児感染免疫 7, 115-118, 1995.

51. Sakaguchi, M. , Inouye, S., Takahashi, Y., Katagiri, S. and Yasueda, H.: Immunoblotting of mite aeroallergens collected with an indoor Burkard sampler. International Journal of Aerobiology 11, 265-268, 1995.

52. Watanabe, M., Sakaguchi, M. , Inouye, S., Miyazawa, H., Mitsuseki, M., Nitta, H., Ohtsuka, R. and Yasueda, H.: Removal of mite allergens from blanket: Comparison of dry cleaning and hot water washing. Journal of Allergy and Clinical Immunology 96, 1010-1012, 1995.

53. Miyazawa, H., Sakaguchi, M. , Inouye, S., Ikeda, K., Honbo, H., Yasueda, H. and Shida, T.: Seasonal changes of mite allergen (Der I and Der II) concentrations in Japanese homes. Annals of Allergy, Asthma and Immunology 76, 170-174, 1996.

54. 岡部俊成，飛田正俊， 阪口雅弘 ，井上　栄，宮沢　博，野呂瀬義彦，竹田幸代，向後俊 昭: 喘息児におけるゴキブリ特異IgE抗体の測定と家庭内ゴキブリアレルゲン量の測定． 日本小児アレルギー学会誌 10, 37-43, 1996.

55. Sakaguchi, M. , Inouye, S., Sasaki, R., Hashimoto, M., Kobayashi, C. and Yasueda, H.: Measurement of airborne mite allergen exposure in individual subjects. Journal of Allergy and Clinical Immunology 97, 1040-1044, 1996.

56. Imaoka, K., Miyazawa, H., Nishihata S., Sakaguchi, M. and Inouye, S.: Effect of pollen exposure on serum IgE and IgG antibody responses in Japanese cedar pollinosis patients. Allergology International 45,159-162, 1996.

57. 高橋裕一，新田裕史，兜　真徳，田村憲治， 阪口雅弘 ，渡辺美香: 盆地におけるスギ花粉とSPMの飛散動態． 日本花粉学会会誌 42, 37-40, 1996.

58. Miyazawa, H., Fukamachi, H., Inagaki, Y., Reese, G., Daul, C.B., Lehrer, S.B., Inouye, S. and Sakaguchi, M. : Identification of the first major allergen of a squid (Todardes pacificus). Journal of Allergy and Clinical Immunology 98, 948-953, 1996.

59. 安枝　浩，奥田　穣，吉田彦太郎，伊藤幸治，馬場　実，飯倉洋治，奥平博一，井上 栄， 阪口雅弘 ，宮本昭正: 我が国におけるアレルゲン標準化の基本方針とスギ花粉アレルゲンエキスの標準化．アレルギー 45, 416-421, 1996.

60. 今井　透，野原　修，片山　昇，遠藤朝彦，井上　栄， 阪口雅弘 ，谷口美文，中川武正， 斉藤三郎: Ｔ細胞応答性を用いた、スギ特異的減感作療法の効果判定．アレルギー 45, 1172-1180, 1996.

61. Sakaguchi, M. , Nakayama, T. and Inouye, S.: Food allergy to gelatin in children with systemic immediate-type reactions, including anaphylaxis, to vaccines. Journal of Allergy and Clinical Immunology 98, 1058-1061, 1996.

62. 長谷川篤彦，辻本　元，小方宗次，岩崎利郎，左向敏紀，久山登美雄，米倉忠夫，橋口　衛， 阪口雅弘 : イヌのアレルゲン特異IgE抗体測定試薬使用成績． 獣医皮膚科臨床 2, 37-45, 1996.

63. Hashimoto, M., Kobayashi, T., Nigi, H., Saito, S., Nakayama, I., Narita, T., Iwata, M., Yasueda, H., Taniguchi, Y., Kurimoto, M., Inouye, S. and Sakaguchi, M. : Responses of monkeys with pollinosis to two major allergens of Japanese cedar pollen. International Archives of Allergy and Immunology 112, 88-92, 1997.

64. Sakaguchi, M. , Yoshida, M., Kuroda, W., Harayama, O., Matsunaga, Y. and Inouye, S.: Systemic immediate-type reactions to gelatin including in Japanese encephalitis vaccines. Vaccine 15, 121-122, 1997.

65. 山中　樹，綿谷靖彦，熊谷卓司，千葉峻三，大野典子，斎藤三郎，菅原由人，栗本文彦， 阪口雅弘 ，井上　栄: 予防接種副反応とゼラチンアレルギーに関する研究．日本医事新報 3795, 37-41, 1997.

66. Sakaguchi, M. , Yamanaka, T., Ikeda, K., Sano, Y., Fujita, H., Miura, T. and Inouye, S.: IgE-mediated systemic reactions to gelatin included in the varicella vaccine. Journal of Allergy and Clinical Immunology 99, 263-264, 1997.

67. 大久保公裕，秋元利香，奥田　稔，八木聡明， 阪口雅弘 ，井上　栄:スギ花粉症に対する舌下免疫療法の基礎 ーヒト口腔粘膜でのスギmajor allergen吸収率ー 耳鼻免疫アレルギー 15, 35-38, 1997.

68. Sakaguchi, M. , Yoshida, T., Asahi, T., Aoki, T., Miyatani, Y. and Inouye, S.:　Development of IgE antibody to gelatin in children with systemic immediate-type reactions to vaccines. Journal of Allergy and Clinical Immunology 99, 720-721, 1997.

69. Yasueda, H., Okuda, M., Yoshida, H., Ito, K., Baba, M., Iikura, Y., Okudaira, H., Inouye, S., Sakaguchi, M. and Miyamoto, T.: A basic policy for allergen standardization in our country and standardization of Japanese cedar (Cryptomeria japonica) pollen extracts. Allergology International 46, 135-140, 1997.

70. Sakaguchi, M. , Hashimoto, M., Nigi, H., Yasueda, H., Takahashi, Y., Watanabe, M., Nagoya, T., Taniguchi, Y., Kurimoto, M. and Inouye, S.: Epitope specificity of IgE antibodies to a major allergen (Cry j 1) of Japanese cedar pollen in sera of humans and monkeys with pollinosis. Immunology 91, 161-166, 1997.

71. Horimoto, T., Takahashi, H., Sakaguchi, M. , Horikoshi, K., Iritani, S., Kazamatsuri, H., Ikeda, K. and Tashiro, M.: A reverse-type sandwich enzyme-linked immunosorbent assay for detecting antibodies to Borna disease virus. Journal of Clinical Microbiology 35, 1661-1666, 1997.

72. Kumagai T., Yamanakaka, T., Wataya, Y., Umetsu, A., Kawamura, N., Ikeda, K., Furukawa, H., Kimura, K., Chiba, S., Saito, A., Sugawara, N., Kurimoto, F., Sakaguchi, M. and Inouye, S.: Gelatin-specific humaral and cellular immune responses in children with immediate- and nonimmediate-type reactions to live measles, mumps, rubella and varicella vaccines. Journal of Allergy and Clinical Immunology 100, 130-134, 1997.

73. Sakaguchi, M. , Nakano, T., Tsujimoto, H., Sasaki, Y., DeBoerd, D.J. and Inouye S.: Specificity of an enzyme-linked immunosorbent assay for dog IgE antibody to Japanese cedar (Cryptomeria japonica) pollen. Allergology International 46, 207-212, 1997.

74. 黒田わか，平野岳毅， 阪口雅弘 : ゼラチンアレルギーによる日本脳炎・麻疹ワクチン接種後の即時型全身副反応の検討． 小児科臨床50, 2041-2044, 1997.

75. Sakaguchi, M. and Inouye, S.: Two patterns of systemic immediate-type reactions to Japanese encephalitis vaccines. Vaccine 16, 68-69, 1998.

76. Sakaguchi, M. , Nakayamam T. and Inouye, S.: Cases of systemic immediate-type urticaria associated with acellular diphtheria-tetanus-pertussis vaccination. Vaccine 16, 1138-1140, 1998.

77. Shirai, T., Hattori, S., Sakaguchi, M. , Inouye, S., Kimura, A., Ebihara, T., Irie, S., Nagai Y. and Hori, H.: The complete cDNA coding sequence for the bovine proα2(I) chain of type I procollagen. Matrix Biology 17, 85-88, 1998.

78. 野原 修，今井 透，遠藤朝彦，永倉仁史，小野幹夫，小沢　仁，森山 寛，斉藤三郎， 阪口雅弘 ，谷口美文: スギ・ヒノキ花粉の共通抗原性におけるCry j 2の関与． 耳鼻免疫アレルギー 16, 26-32, 1998.

79. Hirahara, K., Saito, S., Serizawa N., Sasaki, R., Sakaguchi, M. , Inouye, S., Taniguchi Y., Kaminogawa S. and Shiraishi, A.: Oral administration of a dominant T-cell determinant peptide inhibits allergen-specific TH1 and TH2 cell responses in Cry j 2-primed mice. Journal of Allergy and Clinical Immunology 102, 961-967, 1998.

80. Nakai, S., Nitta, H., Ono, M., Abe, K. and Sakaguchi, M. : Measurement of biological contaminants and particulate matter inside a dwelling in Japan. Indoor Air 9, 41-46, 1999.

81. Sakaguchi, M. , Kaneda, H., and Inouye, S.: A case of anaphylaxis to gelatin included in erythropoietin products. Journal of Allergy and Clinical Immunology 103, 349-350, 1999.

82. Miyazawa, H., Saitoh, S., Kumagai, T., Yamanaka, T., Yasuda, S., Yokota-Tsunetsugu, Y., Inouye, S. and Sakaguchi, M. : Specific IgG to gelatin in children with systemic immediate- and nonimmediate-type reactions to measles, mumps and rubella vaccines.Vaccine 17, 2176-2180, 1999.

83. Kobayashi, C., Hashimoto, M., Nigi, H., Fujimoto, K., Inouye, S. and Sakaguchi, M. : Parasite infection and Japanese cedar pollinosis in monkeys. Veterinary Immunology and Immunopathology 67, 93-100, 1999.

84. Sakaguchi, M. , Hori, H., Ebihara, T., Irie, S., Yanagida, M. and Inouye, S.: Reactivity of the IgE in bovine gelatin-sensitive children to gelatins from various animals. Immunology 96, 286-290, 1999.

85. Kobayashi, C., Nigi, H., Saito, S., Ide, T., Taniguchi, Y., Inouye, S. and Sakaguchi, M. : IgE reactivity and cross-reactivity of Japanese monkeys (Macaca fuscata) to Japanese cedar (Cryptomeria japonica) and cypress (Chamaecyparis obtusa) pollen allergens. Clinical Experimental Allergy 29, 856-861, 1999.

86. Sakaguchi, M. , Kobayashi, C., Inouye, S., Saito, S., Hirahara, K., Shiraishi, A., Konaka, A, Yamada, T. and Nigi, H.: The incidence of Japanese cedar pollinosis and sensitization to the pollen allergens among Japanese monkeys in a troop. Immunology 97, 348-351, 1999.

87. Sakaguchi, M. , Kobayashi, C., Inouye, S., Konaka, A, Yamada, T. and Nigi, H.:Sensitization to grass, ragweed, mugwort pollen allergens in Japanese monkeys (Macaca fuscata): Preliminary report. Clinical Experimental Allergy 29, 1692-1695, 1999.

88. Toriyoshi, H., Shioda, T., Sato, H., Sakaguchi, M. , Eda,Y., Tokiyoshi, S., Kato, K., Nohtomi, K., Kusagawa, S., Taniguchi, K., Shino, T., Kato, A., Foongladda, S., Linkanonsakul, S., Oka, S., Iwamoto, A., Wari, C., Nagai, Y. and Takebe Y.: Sedai virus-based production of HIV type I subtype B and subtype E envelop glycoprotein 120 antigens and their use for highly sensitive detection of subtype-specific serum antibodies. AIDS Research and Human Retroviruses 15, 1109-1120, 1999.

89. Sakaguchi, M. , Hori, H., Hattori, S., Irie, S., Imai, A., Yanagida, M., Miyazawa, H., Toda, M. and Inouye, S.: IgE reactivity to α1 and α2 chains of bovine type I collagen in children with bovine gelatin allergy. Journal of Allergy and Clinical Immunology 104, 695-699, 1999.

90. Masuda, K., Tsujimoto, H., Fujiwara, S., Kurata, K., Hasegawa, A., Yasueda, H., Yamashita, K., DeBoer, D.J., de Weck, A.L. and Sakaguchi, M. : IgE-sensitivity and cross-reactivity to crude and purified mite allergens (Der f 1, Der f 2, Der p 1, Der p 2) in atopic dogs sensitive to Dermatophagoides mite allergens. Veterinary Immunology and Immunopathology 72, 303-313, 1999.

91. Yasueda, H., Saito, A., Sakaguchi, M. , Ide, T., Saito, S., Taniguchi, Y., Akiyama, K. and Inouye, S.: Identification and characterization of a group 2 conifer pollen allergen from Chamaecyparis obtusa, a homologue of Cry j 2 from Cryptomeria japonica. Clinical Experimental Allergy 30, 546-550, 2000.

92. Toda, M., Sato, H., Takebe, Y., Taniguchi, Y., Saito, S., Inouye, S., Takemori, T. and Sakaguchi, M. : Inhibition of IgE response to Japanese cedar pollen allergen (Cry j 1) in mice by DNA immunization: Different outcomes dependent on the plasmid DNA inoculation method. Immunology 99, 179-186, 2000.

93. Masuda, K., Sakaguchi, M. , Fujiwara, S., Kurata, K., Yamashita, K., Odagiri, T., Nakao, Y., Matsuki, N., Ono, K., Watari, T., Hasegawa, A. and Tsujomoto, H.: Positive reactions to common allergens in 42 atopic dogs in Japan. Veterinary Immunology and Immunopathology 73, 193-204, 2000.

94. Sakaguchi, M. , Miyazawa, H. and Inouye, S.: Sensitization to gelatin in children with systemic non-immediate-type reactions to varicella vaccines. Annals of Allergy, Asthma and Immunology 84,341-344, 2000.

95. Sakaguchi, M. and Inouye, S.: IgE sensitization to gelatin: the possible role of gelatin-containing diphtheria-tetanus-acellular pertussis (DTaP) vaccines. Vaccine 18, 2055-2058, 2000.

96. Kingetsu, I., Ohno, N., Hayashi, N., Sakaguchi, M. , Inouye, S. and Saito, S.: Common antigenicity between Japanese cedar (Cryptomeria joponica) pollen and Japanese cypress (Chamaecyparis obtusa) pollen. I. H-2 complex affects cross responsiveness to Cry j 1 and Cha o1 at T and B cell level in mice. Immunology 99, 625-629, 2000.

97. Ohno, N., Ide, T., Sakaguchi, M. , Inouye, S. and Saito, S. Common antigenicity between Japanese cedar (Cryptomeria joponica) pollen and Japanese cypress (Chamaecyparis obtusa) pollen. II. Determination of the cross-reacting T-cell epitope of Cry j 1 and Cha o 1 in mice. Immunology 99, 630-634, 2000.

98. Masuda, K., Tsujimoto, H., Fujiwara S., Kurata K., Hasegawa, A., Taniguchi, Y.,Yamashita K., Yasueda, H., DeBoer, D.J., de Weck, A.L. and Sakaguchi, M. : IgE-reactivity to major Japanese cedar (Cryptomeria japonica) pollen allergens (Cry j 1 and Cry j 2) by ELISA in dogs with atopic dermatitis. Veterinary Immunology and Immunopathology 74,263-270, 2000.

99. 高橋裕一，武田久子，三浦直実，伊籐　聡， 阪口雅弘 ，新田裕史、名古屋隆生: 山形県内の林業従事者のスギ花粉症実態調査．日本花粉学会会誌 46, 23-28, 2000.

100. Sakaguchi, M. , Toda, M., Ebihara, T., Irie, S., Hori, H., Imai, A., Yanagida, M., Miyazawa, H., Ohsuna, H., Ikezawa, Z. and Inouye, S.: IgE antibody to fish gelatin (type I collagen) in patients with fish allergy. Journal of Allergy and Clinical Immunology 106, 579-584, 2000.

101. Tamura, Y., Sasaki, R., Inouye, S., Kawaguchi, J., Serizawa, N., Toda, M., Takemori, T. and Sakaguchi, M. : Identification of a sequential B-cell epitope on major allergen (Cry j 1) of Japanese cedar (Cryptomeria japonica) pollen in mice. International Archives of Allergy and Immunology 123, 228-235, 2000.

102. Masuda, K., Sakaguchi, M. , Saito, S., DeBoer D.J., Fujiwara, S., Kurata, K., Yamashita, K., Hasegawa, A., Ohno, K. and Tsujimoto, H.: In vivo and in vitro tests showing sensitization to Japanese cedar (Cryptomeria japonica) pollen allergen in atopic dogs. Journal of Veterinary Medical Science 62, 995-1000, 2000.

103. Yamashita, K., Masuda, K., Sakaguchi, M. , Odagiri, T., Nakao, Y., Yamaki, M., Hasegawa, A., Matsuo, Y., DeBoer, D.J., Ohno, K. and Tsujimoto, H.: Experimental sensitization with Japanese cedar pollen in dogs. Journal of Veterinary Medical Science 62, 1223-1225, 2000.

104. Saito, S., Hirahara, K., Kawaguchi, J., Serizawa, N., Hino, K., Taniguchi, Y., Kurimoto M., Sakaguchi, M. , Inouye, S. and Shiraishi, A.: Identification of T cell Determinants in Cry j 1 and Cry j 2 of size suitable for peptide immunotherapy against Japanese cedar pollinosis. Annual Report Sankyo Research Laboratory 52, 49-58, 2000.

105. Sakaguchi, M. , Nakayama, T., Fujita, H., Toda, M. and Inouye, S.: Minimum estimated incidence in Japan of anaphylaxis to live virus vaccines including gelatin. Vaccine 19, 431-435, 2001.

106. Masuda, K., Kurata, K., Sakaguchi, M. , Yamashita, K., Hasegawa, A., Ohno, K. and Tsujimoto, H.: Seasonal rhinitis in a cat sensitized to Japanese cedar (Cryptomeria japonica) pollen. Journal of Veterinary Medical Science 63, 79-81, 2001.

107. Sakaguchi, M. , Masuda, K., Toda, M., Inouye, S., Yasueda, H., Taniguchi, Y., Nagoya, T., DeBoerg, J.D. and Tsujimoto, H.: Analysis of the canine IgE-binding epitope on the major allergen (Cry j 1) of Japanese cedar pollen with anti-Cry j 1 monoclonal antibodies. Veterinary Immunology and Immunopathology 78, 35-43, 2001.

108. Sakaguchi, M. , Miyazawa, H. and Inouye, S.: Specific IgE and IgG to gelatin in children with systemic cutaneous reactions to Japanese encephalitis vaccines. Allergy 56, 536-539, 2001.

109. Hirahara, K., Tatuta T., Takatori, T., Ohtsuki, M., Kirinaka, H., Kawaguchi J., Serizawa, N., Taniguchi, Y., Saito, S., Sakaguchi, M. , Inouye, S. and Shiraishi A.: Preclinical evaluation of an immunotherapeutic peptide comprising 7 T-cell determinants of Cry j 1 and Cry j 2, the major Japanese cedar pollen allergens. Journal of Allergy and Clinical Immunology 108, 94-100, 2001.

110. Kimura, H., Shibata, Y., Munakami, H., Hashizume, S., Oba, H., Sakaguchi, M. , Otsuki, K., Kozawa, K. and Kato, M.: Release of IL-4 and IL-5 from human peripheral blood mononuclear cells co-cultured with Japanese cedar pollen antigen in vitro. Cell Biology International 25, 841-844, 2001.

111. Sakaguchi, M. , Nakashima, K., Takahashi, H., Nakayama, T., Fujita, H. and Inouye, S.: Anaphylaxis to Japanese encephalitis vaccine. Allergy 56, 804-805, 2001.

112. Sakaguchi, M. , Yamada, T., Hirahara, K., Shiraishi, A., Saito, S., Miyazawa, H., Taniguchi, Y., Inouye, S. and Nigi, H.: Seasonal changes of humoral and cellular immune responses to Japanese cedar (Cryptomeria japonica) pollen allergens in Japanese monkeys (Macaca fuscata) with pollinosis. Journal of Medical Primatology 30, 112-120, 2001.

113. Sakaguchi, M. , Masuda, K., Yasueda, H., Saito, S., DeBoer, D.J. and Tsujimoto, H.: IgE reactivity and cross-reactivity to Japanese cedar (Cryptomeria japonica) and cypress (Chamaecyparis obtusa) pollen allergens in dogs with atopic dermatitis. Veterinary Immunology and Immunopathology 83, 69-77, 2001.

114. Takahashi, Y., Ohashi, T., Nagano, T., Sakaguchi, M. , Yasueda, H., and Nitta, H.: Possibility of real-time measurement of an airborne Cryptomeria japonica pollen allergen based on the principle of surface plasmon resonance. Aerobiologia 17, 313-318, 2001.

115. Sakaguchi, M. and Inouye, S.: Anaphylaxis to gelatin-containing rectal suppositories. Journal of Allergy and Clinical Immunology 108, 1033-1034, 2001.

116. Masuda, K., Sakaguchi, M. , Saito, S., DeBoer D.J., Yamashita, K., Hasegawa, A., Ohno K. and Tsujumoto, H.: Seasonal atopic dermatitis in dogs sensitive to a major allergen of Japanese cedar (Cryptomeria japonica) pollen. Veterinary Dermatology 13, 55-61, 2002.

117. Siebers, R.W., Lane, J., Yasueda, H., Sakaguchi, M. , Fitzharris, P. and Crane, J.: Reduction of allergen by occlusive covering. Allergy 57, 465, 2002.

118. Sakaguchi, M. , Nakayama, T., Kaku, H., Taniguchi, K., Saito, S., Kimura, A. and Inouye, S.: Analysis of HLA in children with gelatin allergy. Tissue Antigens 59, 412-416, 2002.

119. Toda, M., Kasai, M., Hosokawa, H., Nakano, N., Taniguchi, Y., Inouye, S., Kaminogawa, S., Takemori, T. and Sakaguchi, M. : DNA vaccine using invariant chain gene for delivery of CD4+ T cell epitope peptide derived from Japanese cedar pollen allergen inhibits allergen-specific IgE response. European Journal Immunology 32, 1631-1639, 2002.

120. Ohmori, K., Masuda, K., Sakaguchi, M. , Kaburagi, Y., Ohno, K. and Tsujimoto, H.: A retrospective study on adverse reactions to canine vaccines in Japan. Journal of Veterinary Medical Science 64, 851-853, 2002.

121. Fujimura, M., Ohmori, K., Masuda, K., Tsujimoto, H. and Sakaguchi, M. : Oral allergy syndrome induced tomoto in a dog with Japanese cedar (Cryptomeria japonica) pollinosis. Journal of Veterinary Medical Science 64,1069-1070, 2002.

122. Hori, H., Hattori, S., Inouye, S., Kimura, A., Irie, S., Miyazawa, H. and Sakaguchi, M. : Analysis of the major epitope of the α2 chain of bovine type I collagen in children with bovine gelatin allergy. Journal of Allergy and Clinical Immunology 110, 652-657, 2002.

123. Futamura, N., Mukai, Y., Sakaguchi, M. , Yasueda, H., Inouye, S., Midoro-Horiuti, T.,　Goldblum, R.M. and Shinohara, K.: Isolation and characterization of cDNAs that encode homologs of a pathogenesis-related allergen from Cryptomeria japonica. Bioscience, Biotechnology and Biochemistry 66, 2495-2500, 2002.

124. Yoshitomi, T., Hirahara, K., Kawaguchi, J., Serizawa, N., Taniguchi, Y., Saito, S., Sakaguchi, M. , Inouye, S. and Shiraishi, A.: Three T-cell determinants of Cry j 1 and Cry j 2, the major Japanese cedar pollen antigens, retain their immunogenicity and tolerogenicity in a linked peptide. Immunology, 107, 517-522, 2002.

125. Maeda, S., Okayama, T., Omori, K., Masuda, K., Sakaguchi, M. , Ohno, K., Tsujimoto, H.: Expression of CC chemokine receptor 4 (CCR4) mRNA in canine atopic skin lesion. Veterinary Immunology and Immunopathology 90, 145-154, 2002.

126. 藤村正人，岩崎利郎， 阪口雅弘 : 犬のアトピー性皮膚炎における減感作療法の効果と副作用． 動物臨床医学　11,121-126, 2002.

127. 高橋裕一，安部悦子，三浦直美，荒木龍平，安枝 浩， 阪口雅弘 : 42年生スギにおける花粉中のCry j 1量の年較差およびCry j 1定量法の検討． 日本花粉学会会誌　48, 103-107, 2002.

128. Tamura, Y., Kawaguchi, J., Serizawa, N., Hirahara, K., Shiraishi, A., Nigi, H., Taniguchiu, Y., Toda, M., Inouye, S., Takemori, T. and Sakaguchi, M. : Analysis of sequential IgE-binding epitope of Japanese cedar pollen allergen (Cry j 2) in humans, monkeys and mice. Clinical Experimental Allergy 33, 211-217, 2003.

129. Takahashi, Y., Sakaguchi, M. , von-Pfaler, M. and el-Ghazaly, G.: Relationship between numbers of birch pollen and different particle sizes of the pollen antigens (Bet v 1) in the air in Stockholm, Sweden. Allergology International 52, 111-114, 2003.

130. Ishida, R., Masuda, K., Sakaguchi, M. , Kurata, K., Ohno, K. and Tsujimoto, H.: Antigen-specific histamine release in dogs with food hypersensitivity. Journal of Veterinary Medical Science 65, 435-438, 2003.

131. Takahashi-Omoe, H., Omoe, K., Sakaguchi, M. , Kameoka, Y., Matsushita, S. and Inada,T: Production of virus-specific antiserum corresponding to sequences in the lactate dehydrogenase-elevating virus (LDV) ORF6 protein. Comparative Immunology, Microbiology and Infectious Diseases 27, 47-55, 2004.

132. Takahashi-Omoe, H., Omoe, K., Sakaguchi, M. , Kameoka, Y., Matsushita, S. and Inada, T.: Analysis of protein expression by mammalian cell lines stably expressing lactate dehydrogenase-elevating virus ORF 5 and ORF 6 proteins. Comparative Immunology, Microbiology and Infectious Diseases 27, 81-92, 2004.

133. Kurata, K., Masuda, K., Yasunaga, S., Masuda, K., Sakaguchi, M. , Ohno, K. and Tsujimoto, H.: Immunological findings in 3 dogs clinically diagnosed with allergic rhinitis. Journal of Veterinary Medical Science 66, 25-29, 2004.

134. Maeda, S., Ohmori, K., Kurata, K., Sakaguchi, M. , Masuda, K. Ohno, K. and Tsujimoto, H.: Expression of LacZ gene in canine muscle by intramuscular inoculation of a plasmid DNA. Journal of Veterinary Medical Science 66, 337-339, 2004.

135. Takeno, M., Yoshikawa, H., Kurokawa, M., Takeba, Y., Kashiwakura, J.I., Sakaguchi, M. , Yasueda, H. and Suzuki, N.: Th1-dominant shift of T cell cytokine production, and subsequent reduction of serum immunoglobulin E response by administration in vivo of plasmid expressing Txk/Rlk, a member of Tec family tyrosine kinases, in a mouse model. Clinical Experimental Allergy 34, 965-970, 2004.

136. Hidaka, C., Norose, Y., Nakagawa, Y., Shimizu, M., Takahashi, M., Ohwaki, A., Nohtomi, K., Toda, M., Kusagawa, S., Sakaguchi, M. , Kudo, S., Takebe, Y. and Takahashi, H.: Dermal dendritic cells sensitized with plasmid DNA encoding immunostimulatory sequence by gene gun efficiently prime murine HIV-1-specific CD8+ cytotoxic T lymphocytes. Biomedical Research 25, 83 -91, 2004.

137. Maeda, S., Ohmori, K., Yasuda, N., Kurata, K., Sakaguchi, M. , Masuda, K. Ohno, K. and Tsujimoto, H.: Increase of CC chemokine receptor 4-positive cells in the peripheral CD4+ cells in dogs with atopic dermatitis or experimentally sensitized to Japanese cedar pollen. Clinical Experimental Allergy 34, 1467-1473, 2004.

138. Takasuka, N., Fujii, H., Takahashi, Y., Kasai, M., Morikawa, S., Itamura, S., Ishii, K., Sakaguchi, M. , Ohnishi, K., Ohshima, M., Hashimoto, S., Odagiri, T., Tashiro, M., Yoshikura, H., Takemori, T. and Tsunetsugu-Yokota, Y.: A subcutaneously injected UV-inactivated SARS coronavirus vaccine elicited systemic humoral immunity in mice. International Immunology 16, 1423-1430, 2004.

139. Masuda, K., Sakaguchi, M. , Saito, S., Yasueda, H., Iwabuchi, S., Tsukui, T., Hayashi, N., Nakao, Y., Kurata, K., Maeda, S., Ohno, K. and Tsujimoto, H: Identification of peptides containing T-cell epitopes of Japanese cedar (Cryptomeria japonica) pollen allergen (Cry j 1) in dogs. Veterinary Immunology and Immunopathology 102, 45-52, 2004.

140. Kurata, K., Iwasa, A., Masuda, K., Sakaguchi, M. , Ohno, K. and Tsujimoto, H.: Identification of CpG oligodeoynucleotide sequences that induce IFN-gamma production in canine peripheral blood mononuclear cells. Veterinary Immunology and Immunopathology 102, 441-450, 2004.

141. Ohmori, K., Sakaguchi, M. , Kaburagi, Y., Maeda, S., Masuda, K., Ohno, A. and Tsujimoto, H.: A suspected allergic reactions after vaccination in 85 dogs in Japan. Veterinary Record 156, 87-88, 2005.

142. Miyazawa, H., Sakaguchi, M. , Yasueda, H., Saito, S., Tanaka, K., Nagata, K. and Inouye, S.: Non-IgE-IgG4 antibody to Japanese cedar pollen allergens: Comparison of its prevalence and titers between pollinosis patients and non-patients. Allergology International 54,159-166, 2005.

143. Ohmori, K., Masuda, K., Maeda, S., Kaburagi, Y., Kurata, K., Ohno, K., DeBoer, D.J., Tsujimoto, H. and Sakaguchi, M. : IgE reactivity to vaccine components in dogs that developed immediate-type allergic after vaccination. Veterinary Immunology and Immunopathology 104, 249-256, 2005.

144. Murasugi, T., Nakagami, Y., Yoshitomi, T., Hirahara, K., Yamashita, M., Tanuguchi Y., Sakaguchi, M. and Ito, K.: Oral administration of a T cell epitope inhibits symptoms and reactions of allergic rhinitis in Japanese cedar pollen allergen-sensitized mice. European Journal of Pharmacology 510,143-148, 2005.

145. Olsen, D., Jiang, J., Chang, R., Duffy, R., Sakaguchi, M. , Leigh, S., Lundgard, R., Ju, J., Buschman, F., Truong-Le, V., Pham, B. and Polarek, J.W.: Expression and characterization of a low molecular weight recombinant human gelatin: development of a substitute for animal-derived gelatin with superior features. Protein Expression and Purification 40,346-357, 2005.

146. Ohnishi, K., Sakaguchi, M. , Kaji, T., Akagawa, K., Taniyama, T., Kasai, M., Tsunetsugu-Yokota, Y., Oshima, M., Yamamoto, K., Takasuka, N., Hashimoto, S., Ato, M., Fujii, H., Takahashi, Y., Morikawa, S., Ishii, K., Sata, T., Takagi, H., Itamura, S., Odagiri, T., Miyamura, T., Kurane, I., Tashiro, M., Kurata, T., Yoshikura, H., Takemori, T.: Immunological detection of severe acute respiratory syndrome coronavirus by monoclonal antibodies. Japanese Journal of Infectious Diseases 58, 88-94, 2005.

147. 藤村正人，増田健一， 阪口雅弘 : 掻痒症を伴う犬におけるイベルメクチンおよびミルベマイシンオキシムによる犬疥癬の診断的治療効果． 動物臨床医学　14,81-84, 2005.

148. 藤村正人， 阪口雅弘 : 犬のアトピー性皮膚炎における皮内反応試験と血清特異的IgE検査の比較． 獣医臨床皮膚科　11, 189-192, 2005.

149. Futamura, N., Tani,N., Tsumura, Y., Nakajima, N., Sakaguchi, M. and Shinohara, K.: Characterization of genes for novel thaumatin-like proteins in Cryptomeria japonica. Tree Physiology 26, 51-62, 2006.

150. Futamura, N., Ujiino-Ihara, T., Nishiguchi, M., Kanamori, H., Yoshimura, K., Sakaguchi, M. and Shinohara, K.: Analysis of expressed sequence tags from the pollen of Cryptomeria japonica reveals novel pollen-specific transcripts. Tree Physiology 26, 1517-1528, 2006.

151. Yanagi, U., Ikeda, K., Kagi, N., Sakaguchi, M. and Arashima, Y.: A study on indoor air contaminants related to pets in Japanese dwellings. Journal of Asian Architecture and Building Engineering 5, 355-360, 2006.

152. Ohmori, K., Masueda, K., DeBoer, DJ., Sakaguchi, M. and Tsujimoto, H.: Immunoblotanalysis for IgE-reactive components of fetal calf serum in dogs that developed allergic reactions after non-rabies vaccination. Veterinary Immunology and Immunopathology 115, 166-171, 2007.

153. Fujimura, T., Futamura, N., Midoro-Horiuti, T., Togawa, A., Goldblum, RM., Yasueda, H., Saito, A., Shinohara, K., Masuda, K., Kurata, K. and Sakaguchi, M: Isolation and characterization of native Cry j 3 from Japanese cedar (Cryptomeria japonica) pollen. Allergy 62, 547-553, 2007.

154. 阪口雅弘 ，浦野利晃，安部晶子，作原佐世子，木下淳，高橋一成，仲野友秀，川原井晋平，辻本元: 犬のアトピー性皮膚炎におけるLBSエキスの医薬品併用試験. Visual Veterinary Dermatology 3, 137-143, 2007.

155. Takahashi, Y., Aoyama, M., Yoshitake, M., Abe, E., Ohta, N. and Sakaguchi, M. : Relationship between airborne Cry j 1 and the onset time of the symptoms of Japanese cedar pollinosis patients. Allergology International 56, 277-283, 2007.

156. Yoshitomi, T., Nakagami, Y., Hirahara, K., Taniguchi, Y., Sakaguchi, M. and Yamashita M.: Intraoral Administration of a peptide induces immunological tolerance in Cry j 2-sensitized mice. Journal of Peptide Science 13,499-503, 2007.

157. Ohmori, K., Masuda, K., Kawarai, S., Yasuda, N., Sakaguchi, M. and Tsujimoto, H.: Bovine serum albumin is an IgE-reactive beef component in a dog with beef allergy. Journal of Veterinary Medical Science 69, 865-867, 2007.

158. Ichikawa, S., Fujii, R., Fujiwara, D., Komiyama, Y., Kaisyo, T., Sakaguchi, M. and Konishi, Y.: MyD88 but not TLR2, 4 or 9 is essential for immune modulation by lactic acid bacteria. Bioscience, Biotechnology and Biochemistry 71, 3026-3032, 2007.

159. Takahashi, Y., Aoyama, M., Abe, E., Aita, T., Kawashima, S., Ohta, N. and Sakaguchi, M. : Development of electron spin resonance radical immunoassay for measurement of airborne orchard grass (Dactylis glomerata) pollen antigens. Aerobiologia 24, 53-59, 2008.

160. Nambu, M., Shirai, H., Sakaguchi, M. , Aihara, M. and Takatori, K: Effect of house dust mite-free pillow on clinical course of asthma and IgE level. A randomized, double-blind, controlled study. Pediatric Asthma, Allergy and Immunology 21, 137-144, 2008.

161. Kawarai, S., Masuda, K., Ohmori, K., Matsuura, S., Yasuda, N., Nagata, M., Sakaguchi, M. and Tsujimoto, H: Cultivation and characterization 1 of canine skin-derived mast cells. Journal of Veterinary Medical Science 72, 141-147, 2010.

162. Tobe, S., Kamezaki, H., Watanabe, T., Takaoka, H. and Sakaguchi, M. : Effects of bleach activator, sodium alkyl acyloxybenzene sulfonate, on house dust mites (Dermatophagoides farinae). Journal of Oleo Science 59, 185-190, 2010.

163. Fujimura,T., Yonekura, S., Taniguchi, Y., Horiguchi, S., Saito, A., Yasueda, H., Nakayama, T., Takemori, T., Taniguchi, M., Sakaguchi, M. and Okamoto, Y. :The induced regulatory T-cell level, defined as the proportion of IL10+Foxp3+ cells among CD25+CD4+ leukocytes, is an available therapeutic biomarker for sublingual immunotherapy: A preliminary report. International Archives of Allergy and Immunology 153, 378-387, 2010.

164. Kawarai, S., Ishihara, J., Masuda, K., Yasuda, N., Ohmori, K., Sakaguchi, M. , Asami, Y. and Tsujimoto, H.: Clinical efficacy of a novel elimination diet composed of a mixture of amino acids and potatoes in dogs with non-seasonal pruritic dermatitis. Journal of Veterinary Medical Science 72, 1413-1421, 2010.

165. 稲葉弥寿子，白井秀治，矢上晶子，秋田浩孝， 阪口雅弘 ，水谷 仁，松永佳世子: お好み焼き粉に繁殖したダニによる即時型アレルギーの2 例―Inhibition immunoblot 法による原因抗原の検討と粉の種類によるダニ数およびダニ抗原増加の検討―　日本皮膚科学会雑誌　120，1893- 1900, 2010.

166. Kaburaki, Y., Fujimura, T., Kurata, K., Matsuda, K., Toda, M., Yasueda, H., Chida, K., Kawarai, S. and Sakaguchi, M. : Induction of Th1 immune responses to Japanese cedar pollen allergen (Cry j 1) in mice immunized with Cry j 1 conjugated with CpG oligodeoxynucleotide. Comparative Immunology, Microbiology and Infectious Diseases 34,157-161, 2011.

167. Kawarai, S., Sato, K., Horiguchi, A., Kurata, K., Kiuchi, A., Tsujimoto, H. and Sakaguchi, M. : Potential immunological adjuvant of ‘K’-type CpG-oligodeoxynucleotides enhanced the cell proliferation and IL-6 mRNA expression in canine B cells. Journal of Veterinary Medical Science 73, 177-184, 2011.

168. Okayama, T., Matsuno, Y., Yasuda, N., Tsukui, T., Suzuta, Y., Koyanagi, M., Sakaguchi, M. , Tsujimoto, H., Ishii, Y., Olivry, T. and Masuda, K.: Establishment of a quantitative ELISA for the measurement of an allergen-specific IgE in dogs using anti-IgE antibody cross-reactive to mouse and dog IgE. Veterinary Immunology and Immunopathology 139, 99-106, 2011.

169. Fujimura, T., Yonekura, S., Horiguchi, S., Taniguchi,Y., Saito, A., Yasueda, H., Inamine, A., Nakayama, T., Takemori, T., Taniguchi, M., Sakaguchi, M. and Okamoto, Y.: Increase of regulatory T cells and the ratio of specific IgE to total IgE are potential therapeutic or prognostic biomarkers in two-year sublingual immunotherapy (SLIT) for Japanese cedar pollinosis. Clinical Immunology 139, 65-74, 2011.

170. Miyaji, K., Suzuki, A., Shimakura, H., Takase, Y., Kiuchi, A., Fujimura, M., Kurita, G., Tsujimoto, H. and Sakaguchi, M. : Large-scale survey of adverse reactions to canine non-rabies combined vaccines in Japan. Veterinary Immunology and Immunopathology　145, 447-452, 2012.

171. Kawakami, M., Narumoto, O., Mastuo, Y., Horiguchi, K., Horiguchi, S., Yamashita, N., Sakaguchi, M. , Lipp, M. and Nagase, T. and Yamashita, N.: The role of CCR 7 in allergic airway inflammation induced by house dust mite exposure. Cellular Immunology 275, 24-32, 2012.

172. Narumoto, O., Matsuo, Y., Sakaguchi, M. , Shoji, S., Yamashita, N., Shubert, D., Abe, K., Horiguchi, K., Nagase, T. and Yamashita, N.: Suppressive effects of a pyrazole derivative of curcumin on airway inflammation and remodeling. Experimental and Molecular Pathology 93, 18-25, 2012.

173. Tsukui, T., Sakaguchi, M. , Kurata, K., Maeda, S., Ohmori, K., Masuda, K., Tsujimoto, H. and Iwabuchi, S.: Measurement for canine IgE using canine recombinant high affinity IgE receptor α chain (FcεRIα). Journal of Veterinary Medical Science 74, 851-856, 2012.

174. Kubota, S., Miyaji, K., Shimo Y., Shimakura H., Takase Y., Okamoto, N., Kiuchi, A., Fujimura, M., Fujimura, T., DeBoer, J. D., Tsukui T. and Sakaguchi, M. : IgE reactivity to a Cry j 3, an allergen of Japanese cedar (Cryptomeria japonica) pollen in dogs with canine atopic dermatitis. Veterinary Immunology and Immunopathology 149, 132-135, 2012.

175. Miyaji, K., Yurimoto, T., Saito, A., Yasueda, H., Takase, Y., Shimakura, H., Okamoto, N., Kiuchi, A., Saito, S. and Sakaguchi, M. : Analysis of conformational and sequential IgE epitopes on the major allergen Cry j 2 of Japanese cedar (Cryptomeria japonica) pollen in humans by using monoclonal antibodies for Cry j 2. Journal of Clinical Immunology, 33,977-983, 2013.

176. 藤村正人， 阪口雅弘 : 犬のアトピー性皮膚炎に対する8 日間プロトコールを用いた急速減感作療法の安全性. 獣医アトピー・アレルギー・免疫学会誌　2,14-18,2013.

177. Kanemaki,　N., Tchedre, K.T., Imayasu, M., Kawarai, S., Sakaguchi, M. , Yoshino, A., Itoh, N., Meguro, A., and Mizuki, N.: Dogs and Humans Share a Common Susceptibility Gene SRBD1 for Glaucoma Risk. PLoS One 8: e74372, 2013.

178. 原田晋，白井秀治， 阪口雅弘 : お好み焼き粉, タコ焼き粉に混入したダニによるアレルギーによる眼瞼血管性浮腫の１例.　皮膚臨床　55,1127-33, 2013.

179. Horimoto, T., Gen, F., Murakami, S., Iwatsuki-Horimoto, K., Kato, K., Akashi, H., Hisasue, M., Sakaguchi, M. , Kawaoka, Y., and Maeda, K.: Serological evidence of infection of dogs with human influenza viruses in Japan. Veterinary Record, 174, 96, 2014.

180. 高井敏朗，岡本美孝，大久保公裕，永田真， 阪口雅弘 ，福冨友馬，齋藤明美，安枝浩，増山敬祐: ダニアレルゲンワクチン標準化に関する日本アレルギー学会タスクフォース報告. アレルギー　63:1229-1240,2014.

181. Takai, T., Okamoto, Y., Okubo, K., Nagata, M., Sakaguchi, M. , Fukutomi, Y., Saito, A., Yasueda, H., and Masuyama, K.: Japanese Society of Allergology task force report on standardization of house dust mite allergen vaccines. Allergology International, 64, 181-186, 2015. doi: 10.1016/j.alit.2015.01.005.

182. Horimoto. T., Gen, F., Murakami, S., Iwatsuki-Horimoto, K., Kato, K., Hisasue, M., Sakaguchi, M. , Nidom, C.A., and Kawaoka, Y. Cats as a potential source of emerging influenza virus infections. Virologica Sinica, 30, 221-223, 2015. doi: 10.1007/s12250-015-3580-9.

183. Shigehisa, R., Uchiyama, J., Kato S, Takemura-Uchiyama, I, Yamaguchi, K., Miyata, R., Ujihara, T., Sakaguchi, Y., Okamoto, N., Shimakura, H., Daibata, M., Sakaguchi, M. , and Matsuzaki, S.:Characterization of Pseudomonas aeruginosa phage KPP21 belonging to family Podoviridae genus N4-like viruses isolated in Japan. Microbiology and Immunology, 60, 64-67, 2016. doi: 10.1111/1348-0421.12347.

184. Miyaji, K., Okamoto, N., Saito, S., Yasueda, H., Takase, Y., Shimakura, H., Saito, S., and Sakaguchi, M. : Cross-reactivity between major IgE core epitopes on Cry j 2 allergen of Japanese cedar pollen and relevant sequences on Cha o 2 allergen of Japanese cypress pollen. Allergology and International, 65, 286-292, 2016. doi: 10.1016/j.alit.2016.01.003.

185. 原田　晋，白井秀治，蔵田圭吾，越本知大， 阪口雅弘 ，工藤比等志: 被毛および唾液への感作が認められたジャンガリアンハムスターによるアナフィラキシーの１例. 皮膚臨床　58, 389-396, 2016.

186. Uchiyama, J., Suzuki, M., Kato, S., Miyata, R., Nasukawa, T., Yamaguchi, K., Hirayama, R., Takemura-Uchiyama, I., Ujihara, T., Shimakura, S., Murakami, H., Sakaguchi, Y., Sakaguchi, M. , Matsuzaki, S.: Analyses of short-term antagonistic evolution between Pseudomonas aeruginosa strain PAO1 and phage KPP22 belonging to family Myoviridae genus PB1-like viruses. Applied and Environmental Microbiology 82, 4482-4491, 2016. doi: 10.1128/AEM.00090-16.

187. Uchiyama, J, Takemura-Uchiyama, I., Kato, S., Takeuchi, H., Sakaguchi, Y., Ujihara, T., Daibata, M., Shimakura, H., Okamoto, N., Sakaguchi, M. , Matsuzaki, S.: Screening of KHP30-like prophage in the genome of Helicobacter pylori strain NY40. FEMS Microbiology Letters 363, fnw157, 2016. doi: 10.1093/femsle/fnw157.

188. Shimakura, H., Saito, T., Uchiyama, J., Miyaji, K., Fujimura, M., Masuda, K., Okamoto, N., DeBoer, D.J., Sakaguchi, M. : IgE reactivity to hen’s egg white allergens in dogs with cutaneous adverse food reactions. Veterinary Immunology and Immunopathology 177, 52-57, 2016. doi: 10.1016/j.vetimm.2016.06.003.

189. Murakami, H., Uchiyama, J., Nikaido, S., Sato, R., Sakaguchi, M. , Tsukamoto, K.: Inefficient viral replication of bovine leukemia virus induced by spontaneous deletion mutation on G4 gene. Journal of General Virology 97, 2753-2762, 2016. doi: 10.1099/jgv.0.000583.

190. Horimoto, T., Hiono, T., Mekata, H., Odagiri, T., Lei, Z., Kobayashi, T., Norimine, J., Inoshima, Y., Hikono, H., Murakami, K., Sato, R., Murakami, H., Sakaguchi, M. , Ishii, K., Ando, T., Otomaru, K., Ozawa, M., Sakoda, Y. and Murakami, S.: Nationwide distribution of bovine influenza D virus infection in Japan. Plos one 11, e0163828, 2016. doi: 10.1371/journal.pone.0163828.

191. Tsuboi, M., Watanabe, M., Nibe, K., Yoshimi, N., Kato, A., Sakaguchi, M. , Yamato, O., Tanaka, M., Kuwamura, M., Kushida, K., Ishikura, T., Harada, T., Chambers, J.K., Sugano, S., Uchida, K. and Nakayama, H.: A missense mutation in papillon dog neuroaxonal dystrophy using whole exome sequencing analysis. Plos one 12, e0169002, 2017. doi: 10.1371/journal.pone.0169002.

192. Murakami, H., Asano, S., Uchiyama, J., Sato, R., Sakaguchi, M. and Tsukamoto, K.: Bovine leukemia virus G4 enhances virus production. Virus Research 238:213-217, 2017. doi: 10.1016/j.virusres.2017.07.005.

193. Uchiyama, J., Taniguchi, M., Kurokawa, K., Takemura-Uchiyama, I., Ujihara, T., Shimakura, H., Sakaguchi, Y., Murakami, H., Sakaguchi, M. and Matsuzaki, S.: Adsorption of Staphylococcus viruses S13′ and S24-1 on Staphylococcus aureus strains with different glycosidic linkage patterns of wall teichoic acids. Journal of General Virology 98, 2171-2180, 2017 doi: 10.1099/jgv.0.000865.

194. Nasukawa, T., Uchiyama, J., Taharaguchi, S., Ota, S., Ujihara, T., Matsuzaki, .S, Murakami, H., Mizukami, K. and Sakaguchi, M. : Virus purification by CsCl density gradient using general centrifugation. Archives of Virology 162, 3523-3528, 2017. doi: 10.1007/ s00705-017-3513-z.

195. Ishii, T., Niikura, Y., Kurata, K., Muroi, M., Tanamoto, K., Nagase, T., Sakaguchi, M. and Yamashita, N.: Time dependent distinct roles of Toll-like receptor 4 in a house-dust-mite-induced asthma mouse model. Scandinavian Journal of Immunology 87, e12641, 2018 Jan 16. doi: 10.1111/sji.12641.

196. Ujihara, T., Uchiyama, J., Nasukawa, T., Ando, H., Murakami, H., Ohara, N., Ogawa, M., Yamazaki, T., Daibata, M., Sakaguchi, M. and Matsuzaki, S.: Recovery of mycobacteriophages from archival stocks stored for approximately 50 years in Japan. Archives of Virology 163,1915-1919, 2018. doi: 10.1007/s00705-018-3788-8.

197. Uchiyama, J., Shigehisa, R.,　Nasukawa, T., Mizukami, K.,　Takemura-Uchiyama, I.,　Ujihara, T., Murakami, H., Imanishi, I., Nishifuji, K.,　 Sakaguchi, M. and Matsuzaki, S.: Piperacillin and ceftazidime produce the strongest synergistic phage–antibiotic effect in Pseudomonas aeruginosa. Archives of Virology 163,1941-1948, 2018. doi: 10.1007/s00705-018-3811-0.

198. Murakami, H., Uchiyama, J., Suzuki, C., Nikaido, S., Shibuya, K., Sato, R., Maeda, Y., Tomioka, M., Takeshima, S.N., Kato, H., Sakaguchi, M. , Sentsui, H., Aida, Y. and Tsukamoto, K.: Variations in the viral genome and biological properties of bovine leukemia virus wild-type strains. Virus Research 253, 103-111, 2018. doi: 10.1016/j.virusres.2018.06.005.

199. Uchiyama, J., Mizukami, K., Yahara, K., Kato, S., Murakami, H., Nasukawa, T., Ohara, N., Ogawa, M., Yamazaki, T., Matsuzaki, S. and Sakaguchi, M. : Genome sequences of 12 mycobacteriophages recovered from archival stocks in Japan. Genome Announcements 6, e00472-18, 2018. doi: 10.1128/genomeA.00472-18.

200. Uchiyama, J., Matsui, H., Nasukawa, T., Watanabe, N., Ogata, M., Kato, S, Murakamia, H, Mizukamia, K., Sakaguchi, M. , Matsuzaki, S. and Hanaki, H.: Potential application of bacteriophages in enrichment culture for improved prenatal Streptococcus agalactiae screening. Viruses 10, 552, 2018. doi: 10.3390/v10100552 2018.

201. Furuyama, Y., Takahashi, Y., Noguchi, K., Murakami, H., Sakaguchi, M. , Hisamatsu, S., Usui, T., Yamaguchi, T., Ito, T. and Tsukamoto, K.: Subpopulation primers essential for exhaustive detection of diverse hemagglutinin genes of H5 subtype avian influenza viruses by loop-mediated isothermal amplification method. Journal of Clinical Microbiology 56, e00985-18, 2018. doi: 10.1128/JCM.00985-18.

202. Osumi, T., Shimada, T., Sakaguchi, M. and Tsujimoto,　H.: A double-blind, placebo-controlled evaluation of orally administered heat-killed Enterococcus faecalis FK-23 preparation in atopic dogs. Veterinary Dermatology 30:127-e36.2019. doi: 10.1111/vde.12725.

203. Mizukami, K., Uchiyama, J., Igarashi, H., Murakami, H., Osumi, T., Shima, A., Ishiahra, G., Nasukawa, T., Une, Y. and Sakaguchi, M. : Age-related analysis of the gut microbiome in a purebred dog colony. FEMS Microbiology Letters 366, fnz095 2019. doi: 10.1093/femsle/fnz095.

204. Murakami, H., Todaka, H., Uchiyama, J., Sato, R., Sogawa, K., Sakaguchi, M. and Tsukamoto, K..: A point mutation to the long terminal repeat of bovine leukemia virus related to viral productivity and transmissibility. Virology 537:45-52. 2019. doi: 10.1016/j.virol.2019.08.015.

205. Uchiyama, J., Murakami, H., Sato, R., Mizukami, K., Suzuki, T., Shima, A., Ishihara, G., Sogawa, K. and Sakaguchi, M. . Examination of the fecal microbiota in daury cows infected with bovine leukemia virus. Veterinary Microbiology 240, 108547, 2019. doi.org/10.1016/j.vetmic.2019.108547.

206. Kubomura, A., Sekizuka, T., Onozuka, D., Murakami, K., Kimura, H., Sakaguchi, M. , Oishi, K., Hirai, S., Kuroda, M. and Okabe, N.: Truncated class 1 integron gene cassette arrays contribute to antimicrobial resistance of diarrheagenic Escherichia coli.　BioMed Research International Article ID 4908189, 2020. doi.org/10.1155/2020/4908189.

207. Mizutani,, N., Goto-Koshino, Y., Kurata, K., Fujiwara-Igarashic, A., Sakaguchi, M. , Asadae, M., Ohno, K. and Tsujimoto, H.: Measurement of the concentration of serum soluble interleukin-2 receptor alpha chain in dogs with lymphoma. Veterinary Immunology and Immunopathology 225, 110054, 2020. doi.org/10.1016/ j.vetimm. 2020. 110054.

208. Ishimaru, H., Okamoto, N., Fujimura, M., Miyaji, K., Shimakura, H., Takase, Y., Mizukami, K., Uchiyama, J., DeBoer, D.J. and Sakaguchi, M. : IgE sensitivity to Malassezia pachydermatis and mite allergens in dogs with atopic dermatitis. Veterinary Immunology and Immunopathology 226, 110070, 2020.

209. Tanaka, K., Fukuda, M., Takizawa, T., Shimakura, H., and Sakaguchi, M. : Association analysis of non-synonymous polymorphisms of interleukin-4 receptor-α and interleukin-13 genes in canine atopic dermatitis. Journal of Veterinary Medical Science 82:1253-1259,2020. doi: 10.1292/jvms.20-0301.

210. Murakami, H., Yajima, Y., Sato, F., Kamisuki, S., Taharaguchi, S., Onda, K., Roh, S., Uchiyama, J. Sakaguchi, M. , and Tsukamoto, K.: Development of multipurpose recombinant reporter bovine leukemia virus. Virology 548, 226-235, 2020.

211. Imanishi, I., Uchiyama, J., Mizukami, K., Kamiie, J., Kurata, K., Iyori, K., Fujimura, M., Shimakura, K., Nishifuji, K. and Sakaguchi, M. : IgE reactivity to fish allergens from Pacific cod (Gadus macrocephalus) in atopic dogs. BMC Veterinary Research 16, 341. 2020. doi: 10.1186/s12917-020-02559-1.

212. Nasukawa, T., Sugimoto, R., Uchiyama, J., Takemura-Uchiyama, I., Murakami, H., Fukuda, K., Matsuzaki, S. and Sakaguchi, M. : Purification of membrane vesicles from Gram-positive bacteria using flow cytometry, after iodixanol density-gradient ultracentrifugation. Research in Microbiology 172, 103792, 2021. doi: 10.1016/j.resmic.2020.11.003.

213. 五藤健児、川出雄二郎、白井秀治、 阪口雅弘 、嶋田貴志: ヒノキアレルゲン（Cha a 1）測定: Enzyme-Linked Immunosorbent Assayの確立．医療と検査機器・試薬 44, 187-191, 2021.

214. Yoshida M, Mizukami K, Hisasue M, Imanishi I, Kutara K, Ochiai M, Itoh M, Nasukawa T, Uchiyama J , Tsujimoto H, Sakaguchi M. Anaphylaxis after rabies vaccination for dogs in Japan. Journal of Veterinary Medical Science, 83, 1202-1205, 2021.

215. Murakami H, Murakami-Kawai M, Kamisuki S, Hisanobu S, Tsurukawa Y, Uchiyama J, Sakaguchi M, Tsukamoto K: Specific antiviral effect of violaceoid E on bovine leukemia virus. Virology 562,1-8, 2021.

216. Shimakura H, Nasukawa T, Uchiyama J , Sugimoto R, Imanishi I, Oota S, Mizukami K, Fujimura M, Sakaguchi M. IgE reactivity to milk components in dogs with cutaneous adverse food reactions. Journal of Veterinary Medical Science 83, 1509–1512, 2021.

217. Yoshida M, Mizukami K, Kutara K, M, Nasukawa T, Uchiyama J, Sakaguchi M. New dot-blot method for evaluating the effect of inactivators on mite and Japanese cedar pollen allergens. Bioscience, Biotechnology, and Biochemistry 85, 2089-2092, 2021.

218. Yoshida M, Mizukami K, Hisasue M, Imanishi I, Kurata K, Ochiai M, Itoh M, Nasukawa T, Uchiyama J, Tsujimoto H, Sakaguchi M. Anaphylaxis after vaccination for cats in Japan. Journal of Veterinary Medical Science 84, 149-152, 2022. doi: 10.1292/jvms.21-0437.

219. Yoshida M, Mizukami K, Hisasue M, Imanishi I, Kurata K, Ochiai M, Itoh M, Nasukawa T, Uchiyama J, Tsujimoto H, Sakaguchi M. Anaphylaxis after vaccination for cats in Japan. Journal of Veterinary Medical Science 84, 149-152, 2022. doi: 10.1292/jvms.21-0437.

220. Yoshizaki K, Hirata A, Matsushita H, Sakaguchi M, Yoneji W, Owaki K, Sakai H. Molecular epidemiological study of germline APC variant associated with hereditary gastrointestinal polyposis in dogs: current frequency in Jack Russell Terriers in Japan and breed distribution. BMC Veterinary Research 18, 230, 2022.

221. Uchiyama J, Osumi T, Mizukami K, Fukuyama T, Shima A, Unno A, Takemura-Uchiyama I, Une Y, Murakami H, Sakaguchi M. Characterization of the oral and fecal microbiota associated with atopic dermatitis in dogs selected from a purebred Shiba Inu colony. Lett Appl Microbiol 75,1607-1616. 2022. doi: 10.1111/lam.13828.

222. Imanishi I, Asahina R, Hayashi S, Uchiyama J, Hisasue M, Yamasaki M, Murata Y, Morikawa S, Mizutani T, Sakaguchi M. Serological study of SARS‑CoV‑2 antibodies in Japanese cats using protein‑A/G‑based ELISA. BMC Veterinary Research 18,443, 2022. doi: 10.1186/s12917-022-03527-7.